Kwadwo Asamoah makes his first start for Ghana at the 2012 African Cup of Nations in the Group D clash against Mali.
The attacker plays behind striker Asamoah Gyan as Goran Stevanovic makes three changes to his starting team.
Defender Masahudu Alhassan plays at left back in his Nations Cup debut whiles Jonathan Mensah pairs with John Boye in central defence ahead of the suspended John Mensah.
Starting line-up Adam Kwarasey, John Paintsil, Masahudu Alhassan, Jonathan Mensah, John Boye, Anthony Annan, Andre Ayew, Agyemang Badu, Asamoah Gyan, Kwadwo Asamoah, Sulley Muntari
Subs: Daniel Adjei, Samuel Inkoom, Daniel Opare, Lee Addy, Mohammed Abu, Jordan Ayew, Charles Takyi, Prince Tagoe, Derek Boateng, Ernest Sowah
Suspended John Mensah and Isaac Vorsah