Goalkeeper Fatau Dauda makes his senior debut for the Black Stars as he starts for Ghana in Tuesday's friendly against Liberia.
Coach Kwesi Appiah has also handed Isaac Coffie his maiden start while winger Solomon Asante earns his second cap.
Andre Ayew and younger brother, Jordan, who both featured in the 2013 Nations Cup qualifier against Malawi last Saturday start from the bench.
The Black Stars play the Lone Star to mark Liberia's independence anniversary.
Kick-off of the match was delayed by an hour.
The match originally scheduled to have started 16:00GMT will now start after 17:00GMT due to the late arrival of the home team.
Starting line-up: Fatau Dauda, Samuel Inkoom, Razak Nuhu, John Boye, Jerry Akaminko, Isaac Coffie, Solomon Asante, Derek Boateng, Asamoah Gyan, Kwadwo Asamoah, Christian Atsu.
Subs: Ernest Sowah, Rashid Sumaila, Anthony Annan, Andre Ayew, Jordan Ayew, Abdul Majeed Waris, Richmond Boakye Yiadom.