Ghana's camp is anxiously awaiting the results of Michael Essien’s scan of his knee to determine the extent of the injury.
Essien, who injured his right knee in training on Sunday underwent tests at a hospital in Luanda and could miss a Ghana's clash against Burkina Faso on Tuesday.
Randy Abbey, spokesperson of the Ghana Football Association confirmed the midfielder's injury.
"Michael [Essien] suffered a right knee injury after a collision with a couple of teammates in the training session this morning.
"He was taken to a local hospital for a scan and we'll get the results back tomorrow [Monday] and then have a clearer idea of whether he can play."
Essien has been struggling with fitness after coming off the bench against Ivory Coast last Friday in Cabinda in a game which Ghana lost 3-1.
He arrived in Angola late for the tournament because snow delayed his flight from London and has been struggling to recover from a hamstring injury sustained playing for Chelsea in the Champions League last month.
Ghana are one point behind Burkina Faso and need a win to avoid a first round elimination at the African Nations Cup.