Medeama beat Berekum Chelsea 1-0 in the top-of-the-table clash in the Glo Premier League on Wednesday to return to the top of the standings.
A Theophilus Anobaah header in the 27th minute at the Tarkwa T&A Park ended Chelsea's impressive three-game clean sheet and handed the Mauves all three points.
The result of the tight fixture sees Medeama open a three-point gap at the top ahead of the match-day-5 pairings this weekend.
Medeama travel to the Tamale Stadium to face Real Tamale United but Chelsea will be searching for answers when they take on Hearts of Oak.