There are a number of Accra City derbies to look forward to in the season due to the number of teams in the Greater Accra Region. The Accra based teams include, Accra Hearts of Oak, Accra Great Olympics, Legon Cities and Accra Lions.

The under listed derbies will take place in the course of the season.

Following the qualification of Akyem Oda Kotoku Royals, there is one to anticipate in the Eastern Region. The Eastern derby between Kotoku Royals and Dreams FC is fixed for Match Day Two:

The Western and Western North Regions have four teams in the Premier League. Here is what to expect in the 2022/23 season.

The Brong Ahafo Region is a dominant force on domestic football in the Ghana Premier League as the Region boasts of as many as four Premier League clubs in the elite Division. Two former Champions Aduana FC and Berekum Chelsea have Bechem United and newly promoted Nsoatreman FC to contend with. Here is what to look ahead to in the Brong Ahafo Region.

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